Hematopoietic Cell Transplantation (HCT) Predictions for the Year 2023
نویسندگان
چکیده
منابع مشابه
Hematopoietic Stem Cell Transplantation for Thalassemia
Thalassemia is an autosomal recessive disorder associated with defective synthesis of the α- or β-chain of hemoglobin. For β-thalassemia major patients, therapeutic options are either monthly red cell transfusions and chelation therapy or allogeneic stem cell transplant. Stem cell transplant is the only curative approach and success is inversely correlated with the degree of iron overload and h...
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The introduction and evolution of hematopoietic stem cell transplantation (HSCT) could be traced back to 1950s, to the studies on interactions among irradiation, covering spleen and bone marrow from it and injection of bone marrow cells. Today, HSCT is considered a well-established, effective and promising means of therapy for various malignant and non-malignant medical conditions, both in chil...
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We previously reported that the Charlson Comorbidity Index (CCI) was useful for predicting outcomes in patients undergoing allogeneic hematopoietic cell transplantation (HCT). However, the sample size of patients with scores of 1 or more, captured by the CCI, did not exceed 35%. Further, some comorbidities were rarely found among patients who underwent HCT. Therefore, the current study was desi...
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T he number of allogeneic haemopoietic-cell transplantations (HCT) continues to rise, with more than 25,000 procedures undertaken annually. Several changes in our transplantation practice have contributed to decreased severity of GVHD and organ toxicity, which resulted in improvement in patient outcomes. These changes include the use of reduced intensity conditioning, less toxic conditioning/im...
متن کاملhematopoietic stem cell transplantation for thalassemia
thalassemia is an autosomal recessive disorder associated with defective synthesis of the α- or β-chain of hemoglobin. for β-thalassemia major patients, therapeutic options are either monthly red cell transfusions and chelation therapy or allogeneic stem cell transplant. stem cell transplant is the only curative approach and success is inversely correlated with the degree of iron overload and h...
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ژورنال
عنوان ژورنال: Biology of Blood and Marrow Transplantation
سال: 2020
ISSN: 1083-8791
DOI: 10.1016/j.bbmt.2019.12.692